Identifying selective agonists targeting LXRβ from terpene compounds of alismatis rhizoma
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چکیده
منابع مشابه
Diuretic Activity of Compatible Triterpene Components of Alismatis rhizoma.
Alismatis rhizoma (AR), the dried rhizoma of Alisma orientale Juzepzuk (Alismataceae), is a traditional Chinese medicine. AR is an important part of many prescriptions and is commonly used as a diuretic agent in Asia. This study aimed to evaluate the diuretic effects of total triterpene extract (TTE) and triterpene component compatibility (TCC, the mixture of alisol B 23-acetate, alisol B, alis...
متن کاملProtective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice.
Carbon tetrachloride (CCl4)-induced hepatotoxicity is a common syndrome with simultaneous severe hepatocyte death and acute cholestasis. The purpose of the present study is to investigate the hepatoprotective effect of alisol B 23-acetate (AB23A), a natural triterpenoid from edible botanical Rhizoma alismatis, on acute hepatotoxicity induced by CCl4 in mice, and further to elucidate the involve...
متن کاملFormation and Growth Inhibition of Calcium Oxalate Crystals by Takusha (alismatis Rhizoma)
The aim of this study was to examine the effect of Takusha (Alismatis rhizoma), a Kampou medicine, on the formation, growth and aggregation of calcium oxalate (CaOx) crystals by a seed crystal system, an undiluted urine system and a continuous flow crystallizer system. In the seed crystal method using a metastable solution, the inhibitory effect on aggregation and growth of CaOx crystals was ca...
متن کاملIsolation and characterization of compounds from Nardostachys jatamansi targeting acetylcholinesterase inhibitors based on TLC-bioautography
Background and objectives: The cholinergic deficit correlates with the severity of Alzheimer’s disease. The cholinergic function can be improved by AChE inhibitors blocking this key enzyme in the breakdown of acetylcholine. Based on traditional medicine, during two last decades the use of herbal medicinal substances in dementia therapy has been studied. Nardostachys jataman...
متن کاملOptimization of Extraction Condition for Alisol B and Alisol B Acetate in Alismatis Rhizoma using Response Surface Methodology
Alismatis Rhizoma is a perennial herb originating from the rhizomes of Alisma orientalis (Sam) Juzep and the same species which have been used to treat seborrheic dermatitis, eczema, polydipsia, and pedal edema. We aimed to determine the concentrations of the compounds alisol B and alisol B acetate present in a sample of the herb using high-performance liquid chromatography coupled with a photo...
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ژورنال
عنوان ژورنال: Journal of Molecular Modeling
سال: 2021
ISSN: 1610-2940,0948-5023
DOI: 10.1007/s00894-021-04699-z